In order to achieve the precision and efficient processing of nanocomposite ceramics, the ultrasound-aided electrolytic in process dressing method was proposed. But how to realize grinding parameter optimization, that is, the maximum processing efficiency, on the premise of the assurance of best workpiece quality is a problem that needs to be solved urgently. Firstly, this research investigated the influence of grinding parameters on material removal rate and critical ductile depth, and their mathematic models based on the existing models were developed to simulate the material removal process. Then, on the basis of parameter sensitivity analysis based on partial derivative, the sensitivity models of material removal rates on grinding parameter were established and computed quantitatively by MATLAB, and the key grinding parameter for optimal grinding process was found. Finally, the theoretical analyses were verified by experiments: the material removal rate increases with the increase of grinding parameters, including grinding depth (ap), axial feeding speed (fa), workpiece speed (Vw), and wheel speed (Vs); the parameter sensitivity of material removal rate was in a descending order as ap>fa>Vw>Vs; the most sensitive parameter (ap) was optimized and it was found that the better machining result has been obtained when ap was about 3.73 μm.