Abstract

Background

Sex-differences in presentation and outcomes of ischemic heart disease are well known. Data about gender related mortality comparing men and women after acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI) is conflicting and sparse. The aim of the study was to establish the possible association between gender and in-hospital mortality after ACS treated with PCI in our region.

Methods

ACS patients (3624) undergoing PCI were analyzed. In-hospital mortality was observed in women and men in different age groups.

Results

In-hospital mortality was higher among women than in men (5.1% in men vs. 9.3% in women; p<0.0001). Women more than 80 years old died more frequently in-hospital than their male counterparts (21.2% vs.11.8; p=0.01). The same trend was observed in women aged 50-59. Gender did not predict in-hospital mortality.

Conclusion

Women's in-hospital mortality is higher than in men. Women older than 80 years die more often as their age-matched male patients. Special attention should be paid to women with ACS since they are older, with more comorbidities, and therefore, high risk.