spontaneous t cell proliferation: a physiologic process to create and maintain homeostatic balance and diversity of the immune system
Abstract
Naive T lymphocytes undergo heterogeneous proliferative responses when introduced into lymphopenic hosts, referred to as “homeostatic proliferation” and “spontaneous proliferation.” Spontaneous proliferation is a unique process through which the immune system generates memory phenotype cells with increasing T cell receptors repertoire complexity. Here, the mechanisms that initiate and control spontaneous proliferation are discussed.
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251133
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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
251133
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10.3389/fimmu.2018.00547
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Scimatic Chain (ID: 481)
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