The motif of Medusa had significant importance in Roman visual culture, reflecting the comprehension of ancient people about this frightful being. Visual material from the territory of the Central Balkans suggests a widely known understanding and belief of the protective as well as apotropaic functions of Medusa. The motif of Medusa i.e. the Gorgoneion, was one of the well known and most represented motifs in architecture, funerary art and artiminori and a widely appreciated decoration of jewellery, signifying the importance of Medusa’s protection for people, especially for women. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 47018: IRS - Viminacium, roman city and military legion camp - research of material and non-material culture of inhabitants by using the modern technologies of remote detection, geophysics, GIS, digitalization and 3D visualization]