Multisensor information fusion, when applied to fault diagnosis, the time-space scope, and the quantity of information are expanded compared to what could be acquired by a single sensor, so the diagnostic object can be described more comprehensively. This paper presents a methodology of fault diagnosis in rotating machinery using multisensor information fusion that all the features are calculated using vibration data in time domain to constitute fusional vector and the support vector machine (SVM) is used for classification. The effectiveness of the presented methodology is tested by three case studies: diagnostic of faulty gear, rolling bearing, and identification of rotor crack. For each case study, the sensibilities of the features are analyzed. The results indicate that the peak factor is the most sensitive feature in the twelve time-domain features for identifying gear defect, and the mean, amplitude square, root mean square, root amplitude, and standard deviation are all sensitive for identifying gear, rolling bearing, and rotor crack defect comparatively.