effects of adjuvant therapy with anluohuaxian capsule on serum inflammatory factors, hepatic fibrosis indexes and immune function in patients with hepatitis b cirrhosis
Abstract
Objective: To investigate the effect of adjuvant therapy with anluohuaxian capsule on the
treatment of hepatitis B cirrhosis, and its influence on serum inflammatory factors, liver
fibrosis indexes and immune function. Methods: A total of 112 cases of hepatitis B cirrhosis
patients were divided into the control group (n=55) and observation group (n=57) according to
the random data table, patients in the two groups were given routine treatment, on this basis,
the control group received the treatment of Adefovir Dipivoxil Tablets, and the observation
group was treated with Adefovir Dipivoxil Tablets combined with Anluo Huaxian pill
treatment, two groups were treated for 48 weeks. The levels of serum inflammatory factors,
liver fibrosis indexes and immune function indexes of the two groups were compared before
and after treatment. Results: Before treatment, There was no significant difference between
the two groups of TNF-α, IL-6, hs-CRP, IVC, HA, PIIIP, LN, CD3+
, CD4+
, CD8+
and CD4+
/
CD8+
levels. After treatment, TNF-α, IL-6, hs-CRP, IVC, HA, PIIIP, LN, CD3+
, CD4+
,
CD8+
and CD4+
/CD8+
levels in the observation group and control group were significantly
lower than those before treatment in the same group, and levels in the observation group after
treatment were significantly lower than the control group; Compared with the group before
treatment, the levels of CD3+
, CD4+
and CD4+
/CD8+
of two groups after treatment were
significantly increased, and the observation group was significantly higher than the control
group. Conclusion: Adjuvant therapy with anluohuaxian capsule on the treatment of hepatitis
B cirrhosis, can effectively reduce the inflammatory stress reaction, reduce the level of serum
liver fibrosis index and improve the immune function, and has important clinical value.
Keywords
chemistry
hemodynamics
cytokines
dexmedetomidine
chronic heart failure
stress response
liver fibrosis index
myelin basic protein
brain trauma
acute phase protein
low molecular weight heparin
respiratory failure
propofol
clinical endocrinology
diseases of the endocrine glands
neuron specific enolase
inflammatory cytokinesmedicine
s100b protein
d-two polymermedicine
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Citation
ID:
245044
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