In this paper an investigation of mixed convection from vertical heated channel is undertaken. The aim is to explore the heat transfer obtained by adding a forced flow, issued from a flat nozzle located in the entry section of a channel, to the up-going fluid along its walls. Forced and free convection are combined studied in order to increase the cooling requirements. The study deals with both symmetrically and asymmetrically heated channel. The Reynolds number based on the nozzle width and the jet velocity is assumed to be 3 103 and 2.104; whereas, the Rayleigh number based on the channel length and the wall temperature difference varies from 2.57 1010 to 5.15 1012. The heating asymmetry effect on the flow development including the mean velocity and temperature the local Nusselt number, the mass flow rate and heat transfer are examined.