The following abstract contains 150 words: Studies regarding compound word processing have centred on Noun-noun words, which exhibit endocentricity. Nevertheless, other compound types, such as Spanish Verb-noun compounds, exhibit morphological particularities such as exocentricity, verb argument structure, and metaphorical features, increasing the attributes that may influence compound processing. We analysed whether these traits influenced Spanish Verb-noun compound processing. A lexical decision task was administrated with electroencephalogram (EEG) recording. Following differences in argument structure and metaphorical traits, three compound types were presented: Agentives, Locatives, and Metaphoricals. Locatives were responded worse and slower than Agentives. Metaphoricals elicited increases in the P300 and P600-like components. Thus, verb argument structure and metaphorical processes influence Spanish Verb-noun compound processing. Similarly to endocentric English Noun-noun compounds, processing Spanish Verb-noun compounds involves specific conceptual operations. These conceptual combinations appear to be determined by the projection of verb argument structure and the mapping and assignation of thematic roles.