We pursued the following three interconnected points: (1) there are unexplored opportunities for resilience scholars from different disciplines to cross-inspire and inform, (2) a systems perspective may enhance understanding of human resilience in health and social settings, and (3) resilience is often considered to be fractal, i.e., a phenomenon with recognizable or recurring features at a variety of scales. Following a consideration of resilience from a systems perspective, we explain how resilience can, for analytic purposes, be constructed at four scales: micro, meso, macro, and cross-scale. Adding to the cross-scale perspective of the social-ecological field, we have suggested an analytical framework for resilience studies of the health field, which incorporates holism and complexity by embracing an ecological model of cognition, something supported by empirical studies of organizations in crisis situations at various spatial as well as temporal scales.