Liquid Argon Time Projection Chambers are very promising detectors for neutrino and astroparticle physics due to their high granularity, good energy resolution and 3D imaging, allowing for a precise event reconstruction. ICARUS T600 is the largest liquid Argon (LAr) TPC detector ever built (~600 ton LAr mass) and is presently operating underground at the LNGS laboratory. This detector, internationally considered as the milestone towards the realization of the next generation of massive detectors (~tens of ktons) for neutrino and rare event physics, has been smoothly running since summer 2010, collecting data with the CNGS beam and with cosmics. The status of this detector will be shortly described together with the intent to adopt the LAr TPC technology at CERN as a possible solution to the sterile neutrino puzzle.