In vivo experimental analysis of the stabilization of human bone fractures involves many issues, thus a virtual simulation of the mechanical behavior of assembly bone-plate-screws is more accessible. The paper presents a study of modeling and numerical analysis of four stabilization systems consisting of Screw-type Locking Compression Plates.The objective of the numerical analysis was to determine areas of maximum deformations and stresses occurring in bone-stabilization system under the action of certain loads. Based on the results obtained by numerical analysis for different plates, different fixing conditions, different loads, and two fracture types a comparison was performed, and the most favorable one was selected for the considered fractures. Based on the conclusions developed from the carried out research design of new models of stabilization systems depending on the fracture type will be performed.