Background and Aims: Marital satisfaction, one of the most important determinants of healthy family functioning. Therefore dealing with components that can be useful is very important. Spiritual health is one of them. This study aimed to investigate the relationship between spiritual health and marital satisfaction. Method: The research was cross-sectional and correlational study, 122 married women referred to health centers in Karaj using a convenience sampling participated in the study. Enrich marital satisfaction questionnaire and Palutzian Ellison spiritual health questionnaire were used. To analyze the data was used SPSS version 16. Descriptive statistics, Pearson correlation coefficient, regression, t-test and ANOVA was used to achieve the goals and answer research questions. Results: The results showed there were significant correlation between marital satisfaction and spiritual well being in married women ( (P<0/001). The results showed that the mean score of spiritual well-being was moderate (14 ± 99) and the mean score of marital satisfaction was also moderate (29 ± 164). There was a significant relationship between mean score of satisfaction and age, age of husband, husband's and wife's education, (p <0.05). Conclusion: According to the results of this study to improve the quality of life of women and men and marital satisfaction, spiritual health should be considered.