immune response modulation by vitamin d: role in systemic lupus erythematosus.

immune response modulation by vitamin d: role in systemic lupus erythematosus.

;Mirentxu eIruretagoyena;Daniela eHirigoyen;Rodrigo eNaves;Paula Isabel Burgos
sudebno-meditsinskaia ekspertiza 2015 Vol. 6 pp. -
187
eiruretagoyena2015frontiersimmune

Abstract

Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity and possible effects of supplementation in disease treatment.

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236289
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10.3389/fimmu.2015.00513
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