The present article studies an ethno-social prejudice that people of European ancestry (both Whites and Mulattoes) developed towards black slaves and their descendants in the Hispanic Worlds from late 15th century. To analyze this phenomenon, we have gathered many manifestations that reflected its existence at both sides of the Atlantic, so we can distinguish its ideological and mental characteristics as we aim to determine its extension and the socio-cultural consequences it had on the communities it appeared.