Introduction Based on Task Group No. 43 (TG-43U1) recommendations, water phantom is proposed as a reference phantom for the dosimetry of brachytherapy sources. The experimental determination of TG-43 parameters is usually performed in water-equivalent solid phantoms. The purpose of this study was to determine the conversion factors for equalizing solid phantoms to water. Materials and Methods TG-43 parameters of low- and high-energy brachytherapy sources (i.e., Pd-103, I-125 and Cs-137) were obtained in different phantoms, using Monte Carlo simulations. The brachytherapy sources were simulated at the center of different phantoms including water, solid water, poly(methyl methacrylate), polystyrene and polyethylene. Dosimetric parameters such as dose rate constant, radial dose function and anisotropy function of each source were compared in different phantoms. Then, conversion factors were obtained to make phantom parameters equivalent to those of water. Results Polynomial coefficients of conversion factors were obtained for all sources to quantitatively compare g(r) values in different phantom materials and the radial dose function in water. Conclusion Polynomial coefficients of conversion factors were obtained for all sources to quantitatively compare g(r) values in different phantom materials and the radial dose function in water.