An experimental investigation of metrological characteristics of designed Universal Sensors and Transducers Interface (USTI-MOB) integrated circuit working in the phase shift measuring mode is described in the article. The USTI-MOB uses the novel patented method for phase difference (phase shift) measurements between two harmonic (sine wave) or rectangular pulse signals. Experiments have confirmed the high metrological performance in low and inferable frequency ranges up to 0.25 Hz at low power consumption (0.35 mA current consumption at Vcc = 1.8 V). The optimal trade-off between accuracy, power consumption and communication speed has achieved. In order to decrease the absolute error in 4 times at least, the standard series of USTI IC is recommended for the usage. Due to the low power consumption, the USTI-MOB is very suitable for various portable measuring instruments, DAQ systems, smart sensor systems, etc.