cathepsin a activity of a parietal thrombus of an abdominal aortic aneurysm
;Anna Worowska;Marek Gacko;Marta Siergiejuk
reviews on recent clinical trials2011Vol. 49pp. 10-12
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worowska2011foliacathepsin
Abstract
We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z–Phe–Ala. It was lower on Z–Phe–Phe, Z–Glu–Tyr, Z–Glu–Phe, Z–Gly–Phe, and the lowest activity was on Z–Gly–Ala. We conclude that cathepsin A’s activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity. <i>(Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 1, pp. 10–12)