cathepsin a activity of a parietal thrombus of an abdominal aortic aneurysm

cathepsin a activity of a parietal thrombus of an abdominal aortic aneurysm

;Anna Worowska;Marek Gacko;Marta Siergiejuk
reviews on recent clinical trials 2011 Vol. 49 pp. 10-12
151
worowska2011foliacathepsin

Abstract

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z&#8211;Phe&#8211;Ala. It was lower on Z&#8211;Phe&#8211;Phe, Z&#8211;Glu&#8211;Tyr, Z&#8211;Glu&#8211;Phe, Z&#8211;Gly&#8211;Phe, and the lowest activity was on Z&#8211;Gly&#8211;Ala. We conclude that cathepsin A&#8217;s activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity. <i>(Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 1, pp. 10&#8211;12)

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225712
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