numerosol a–d, new cembranoid diterpenes from the soft coral sinularia numerosa
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numerosol a–d, new cembranoid diterpenes from the soft coral sinularia numerosa

;Yen-Ju Tseng;Yuan-Chien Yang;Shang-Kwei Wang;Chang-Yih Duh
jixie gongcheng xuebao/journal of mechanical engineering 2014 Vol. 12 pp. 3371-3380
202
tseng2014marinenumerosol

Abstract

Four new cembrane-type diterpenes; numerosol A–D (1–4); along with a known steroid; gibberoketosterol (5); were isolated from the Taiwanese soft coral Sinularia numerosa. The structures of these metabolites were determined by extensive analysis of spectroscopic data. Gibberoketosterol (5) exhibited cytotoxicity against P-388 (mouse lymphocytic leukemia) cell line with an ED50 of 6.9 μM.

Keywords

soft coral cytotoxicitybiology (general) gibberoketosterol

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DOI:
10.3390/md12063371
URL:
http://www.mdpi.com/1660-3397/12/6/3371

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ID: 225672
Ref Key: tseng2014marinenumerosol
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225672
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