the antiallodynic action of pregabalin may depend on the suppression of spinal neuronal hyperexcitability in rats with spared nerve injury

the antiallodynic action of pregabalin may depend on the suppression of spinal neuronal hyperexcitability in rats with spared nerve injury

;Lei Ding;Jie Cai;Xiang-Yang Guo;Xiu-Li Meng;Guo-Gang Xing
chemistryselect 2014 Vol. 19 pp. 205-211
153
ding2014painthe

Abstract

BACKGROUND: Pregabalin (PGB) is a novel antiepileptic drug and is also used as a first-line medication for the treatment of neuropathic pain. However, the mechanisms of its analgesic effects remain largely unknown.

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