chronic graft versus host disease and nephrotic syndrome

chronic graft versus host disease and nephrotic syndrome

;Samia Barbouch;Hanene Gaied;Khaoula Ben Abdelghani;Rim Goucha;Amel Lakhal;Lamia Torjemen;Fethi Ben Hamida;Ezzedine Abderrahim;Hedi Ben Maiz;HafedhHedri;Khedher Adel
15th ibero-american conference on software engineering, cibse 2012 2014 Vol. 25 pp. 1062-1064
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barbouch2014saudichronic

Abstract

Disturbed kidney function is a common complication after bone marrow transplantation. Recently, attention has been given to immune-mediated glomerular damage related to graft versus host disease (GVHD). We describe a 19-year-old woman who developed membranous glomerulonephritis after bone marrow transplantation (BMT). Six months later, she developed soft palate, skin and liver lesions considered to be chronic GVHD. Fifteen months after undergoing BMT, this patient presented with nephrotic syndrome. A renal biopsy showed mem-branous glomerulonephritis associated with a focal segmental glomerulosclerosis. She was started on corticosteroid treatment with good outcome.

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