Objective 　To discuss the relative and independent risk factors in ectopic pregnancy. Methods 　The clinical data of 870 patients with ectopic pregnancy, admitted from 2005 to 2012, were retrospectively analyzed, with 800 cases of normal pregnancy serving as control. Monofactorial correlation analysis was used to analyze the related risk factor, and logistic regression analysis was used to analyze the independent risk factor. Results 　Pelvic adhesion, previous operation, cesarean section delivery, number of pregnancy, artificial abortion, medical abortion, in vitrofertilization and embryo replacement (IVF-ER), and placement of intrauterine device (IUD) are the risk factors of ectopic pregnancy, pelvic adhesion, artificial abortion, operation, number of pregnancies and IUD are the independent risk factors, and pelvic adhesion is the major risk factor. Conclusion 　Avoidance of unexpected pregnancy as possible, reduction of the number of artificial abortion, prevention and treatment of genital duct inflammation, and standardization of pelvic operation may reduce the incidence of ectopic pregnancy.