facile and efficient conjugate additions of b-dicarbonyl compounds and nitroalkanes to 4-aryl-4-oxobut-2-enoates

facile and efficient conjugate additions of b-dicarbonyl compounds and nitroalkanes to 4-aryl-4-oxobut-2-enoates

;XIN LV;YAOHONG ZHANG;LIEJIN ZHOU;XIAOXIA WANG
meditsinskaia radiologiia 2011 Vol. 76 pp. 947-954
63
lv2011journalfacile

Abstract

Facile and efficient conjugate additions of carbon nucleophiles, such as b-dicarbonyl compounds and nitroalkanes, to 4-aryl-4-oxobut-2-enoates have been achieved under simple base catalysis. A variety of multi-functional g-keto esters could be conveniently obtained in good to excellent yields with complete regioselectivity.

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