Objectives: To establish the risk factors associatedwith infectious complications after vaginalor abdominal planned hysterectomy. Methodology:Study of cases and controls Place:Gynaecology Department and Septic Unit,Clinica San Pedro Claver, Bogotá, Colombia.SAMPLE: 565 patients (115 cases and 450 controls)who had planned hysterectomy for anybenign or pre-malign cause. The cases weredefined as patients who enter the septic service with diagnosis of any septic condition. Results:Among the analysed risk factors that werestatistically meaningful are the diagnosis ofdiabetes mellitus (OR 6.01 CI: 2.03-18.15),more than 3 deliveries (OR1.73 CI: 1.10-2.73),IUT use(OR3.94 CI: 2.42-6.43), vaginaldischarge (OR 5.13 CI: 3.16-8.33) or presenceof swelling previous to the surgery (OR 3.76IC: 2.37-5.97), and use of prophylactic anticoagulation(OR 3.37 CI: 2.15-5.28) Conclusion:The presence of vaginal discharge and swellingin vaginal cytology are the important predictorsof infectious morbidity that can be correctedprior to the surgery.