exogenous and endogenous opioid-induced pain hypersensitivity in different rat strains

exogenous and endogenous opioid-induced pain hypersensitivity in different rat strains

;Emilie Laboureyras;Frédéric Aubrun;Maud Monsaingeon;Jean-Benoît Corcuff;Jean-Paul Laulin;Guy Simonnet
chemistryselect 2014 Vol. 19 pp. 191-197
142
laboureyras2014painexogenous

Abstract

BACKGROUND: Opioid-induced hyperalgesia (OIH) is a recognized complication of opioid use that may facilitate the development of exaggerated postoperative pain.

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