Assessment of expected loss and damage caused by earthquakes and secondary technological accidents are of primary importance for the development and implementation of preventive measure plans, as well as for emergency management just after the disaster. The paper addresses the procedures for estimations of loss caused by strong events and secondary hazards with information technology application. Examples of individual seismic risk zoning at Russian federal and regional levels are given, as well as that of scenario earthquakes consequences estimation, taking into account secondary technological hazards.