The article considers the economic conditions for the formation of the quality of life for a regional society, the Republic of Tatarstan. This research bases on comparing the economic indicators of the development of the region and the results of a public opinion survey on the economic components of the quality of life and the material well-being of a family. Statistical indicators of the economic development in the Republic of Tatarstan over the past decade show a positive dynamics of growth, while the satisfaction of the population with the main components of economic well-being does not always has a similar picture. Our studies show that the material well-being of a family and an individual citizen is determined not only by the growth of the aggregate income of the family, but also by such macroeconomic indicators as the level of inflation, the growth of tariffs for utilities. Consequently, the social well-being of the population is more correlated with the real incomes of a family than from macroeconomic growth indicators.