a fast, sensitive and accurate high resolution melting (hrm) technology-based assay to screen for common k-ras mutations
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a fast, sensitive and accurate high resolution melting (hrm) technology-based assay to screen for common k-ras mutations

;D. Kramer;F. B. Thunnissen;M. I. Gallegos-Ruiz;E. F. Smit;P. E. Postmus;C. J. L. M. Meijer;P.J.F. Snijders;D. A. M. Heideman
journal of the serbian chemical society 2009 Vol. 31 pp. 161-167
230
kramer2009cellulara

Abstract

Background: Increasing evidence points to a negative correlation between K-ras mutations and patient’s response to, or survival benefit after, treatment with EGFR-inhibitors. Therefore, rapid and reliable assays for mutational analysis of the K-ras gene are strongly needed.

Keywords

neoplasms Oncology including cancer and carcinogenscytology tumors

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DOI:
10.3233/CLO-2009-0466
URL:
http://dx.doi.org/10.3233/CLO-2009-0466

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ID: 196300
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