In this work, we have investigated the effect of partial slip on hydromagnetic boundary layer flow in porous medium over a stretching surface with space and temperature dependent internal heat generation/absorption, thermal radiation and wall mass transfer (suction/blowing). The basic boundary layer equations for momentum and heat transfer, which are non-linear partial differential equations are converted into non-linear ordinary differential equations by means of similarity transformations. The dimensionless governing equations for this investigation are solved analytically using hypergeometric functions. The results are carried out for prescribed surface temperature (PST) and prescribed power law surface heat flux (PHF). The effect of partial slip parameter with magnetic parameter, porosity parameter, wall mass transfer parameter (suction/blowing), space and temperature dependent internal heat generation/absorption parameter, Prandtl number and radiation parameter on velocity and temperature distributions are depicted graphically and are analyzed in detail.