The Jesuitic reductions in Paraguay were characterized for establishing a place of direct and continuous contact between Christianity and the natives. The priests seeked to offer Indians guidance on an everyday basis to the Christian life through masses, preaching, teaching and sacraments. Sacramental confession, above all else, had a fundamental role since it served not only as a way of redemption to the sinners, but also as a way for priests to keep themselves informed about the progress of evangelization in the reductional environment: they believed that the more confessions that were performed, the more widespread would Christian religion be in native life. The present article will analyze how the assimilation of the sacrament came to be among the Indians and how Ignatian discourse adapts itself to the difficulties that arise.