We illustrate the ability to monitor the status of snow water content over large areas by using a spatially distributed snow accumulation and ablation model that uses data from a weather forecast model in the upper Colorado Basin. The model was forced with precipitation fields from the National Weather Service (NWS) Multi-sensor Precipitation Estimator (MPE) and the Tropical Rainfall Measuring Mission (TRMM) data-sets; remaining meteorological model input data were from NOAA's Global Forecast System (GFS) model output fields. The simulated snow water equivalent (SWE) was compared to SWEs from the Snow Data Assimilation System (SNODAS) and SNOwpack TELemetry system (SNOTEL) over a region of the western US that covers parts of the upper Colorado Basin. We also compared the SWE product estimated from the special sensor microwave imager (SSM/I) and scanning multichannel microwave radiometer (SMMR) to the SNODAS and SNOTEL SWE data-sets. Agreement between the spatial distributions of the simulated SWE with MPE data was high with both SNODAS and SNOTEL. Model-simulated SWE with TRMM precipitation and SWE estimated from the passive microwave imagery were not significantly correlated spatially with either SNODAS or the SNOTEL SWE. Average basin-wide SWE simulated with the MPE and the TRMM data were highly correlated with both SNODAS (r = 0.94 and r = 0.64; d.f. = 14 – d.f. = degrees of freedom) and SNOTEL (r = 0.93 and r = 0.68; d.f. = 14). The SWE estimated from the passive microwave imagery was significantly correlated with the SNODAS SWE (r = 0.55, d.f. = 9, p = 0.05) but was not significantly correlated with the SNOTEL-reported SWE values (r = 0.45, d.f. = 9, p = 0.05).The results indicate the applicability of the snow energy balance model for monitoring snow water content at regional scales when coupled with meteorological data of acceptable quality. The two snow water contents from the microwave imagery (SMMR and SSM/I) and the Utah Energy Balance forced with the TRMM precipitation data were found to be unreliable sources for mapping SWE in the study area; both data sets lacked discernible variability of snow water content between sites as seen in the SNOTEL and SNODAS SWE data. This study will contribute to better understanding the adequacy of data from weather forecast models, TRMM, and microwave imagery for monitoring status of the snow water content.