malignant triton tumor of the sciatic nerve as a secondary malignancy after extended field radiotherapy and chemotherapy of hodgkin's disease

malignant triton tumor of the sciatic nerve as a secondary malignancy after extended field radiotherapy and chemotherapy of hodgkin's disease

;Mirko Nitsche;Michael Reible;Karl-Heinz Pflüger;Markus Bergmann;Robert Michael Hermann
multi-span large bridges - proceedings of the international conference on multi-span large bridges, 2015 2014 Vol. 7 pp. 239-245
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nitsche2014casemalignant

Abstract

Late effects of therapy for Hodgkin's disease include secondary malignancies like leukemia, lymphoma or solid tumors developing after long periods of latency. Ionizing radiation often causes the last group. The highest risks have been described for induced breast and lung cancers. We are the first to report a malignant triton tumor (MTT) as a secondary malignancy after radiotherapy and chemotherapy for Hodgkin's lymphoma. MTT is a very rare subtype of malignant peripheral nerve sheath tumors with rhabdomyoblastic differentiation and an aggressive course of disease.

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