bilateral primary adrenal non-hodgkin′s lymphoma without adrenal insufficiency

bilateral primary adrenal non-hodgkin′s lymphoma without adrenal insufficiency

;William Greg Simpson;Paurush Babbar;Lynnetta Faith Payne
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2015 Vol. 7 pp. 259-261
167
simpson2015urologybilateral

Abstract

We are presenting a rare case of bilateral adrenal non-Hodgkin′s lymphoma (NHL) that presented as a primary malignancy. An 83-year-old man presented with newly discovered bilateral adrenal incidentalomas, fatigue, and 30 pound weight loss. Of the 116 cases of primary adrenal NHL reported, over half have presented bilaterally and occur with adrenal insufficiency. Therefore, the finding of bilateral adrenal masses requires an urgent work-up of the functional status of the adrenal gland as well as a thorough analysis of the imaging characteristics seen on noncontrast computed tomography (CT) in order to maximize patient survival. Adrenal function testing was normal. Repeat CT imaging revealed rapidly growing lesions with high attenuations; both masses >10 HU. Histological examination of core biopsies discovered malignant lymphoma with no known past history of lymphoma. Our case coincides with the literature, which states that a mass with attenuation >10 HU in the adrenal glands has a high risk of malignancy.

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Ref Key: simpson2015urologybilateral
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