dual function microtubule- and mitochondria-associated proteins mediate mitotic cell death
Abstract
Background: Survival and evolution of aneuploid cells after an asymmetric segregation of chromosomes at mitosis may be the common initiating event and underlying cause of the genetic diversity and adaptability of cancers. We hypothesize that mechanisms exist to detect impending aneuploidy and prevent it before completion of an aberrant mitosis.
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183527
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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
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183527
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10.3233/CLO-2009-0484
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