life-threatening cardiac manifestations of pheochromocytoma

life-threatening cardiac manifestations of pheochromocytoma

;Luiz R. Leite;Paula G. Macedo;Simone N. Santos;Luiz Quaglia;Cezar E. Mesas;Angelo De Paola
Frontiers in pharmacology 2010 Vol. 2010 pp. -
99
leite2010caselife-threatening

Abstract

Pheochromocytoma is a catecholamine-secreting tumor of the adrenal glands, usually with benign manifestations, whose typical clinical presentation includes the triad of headache, palpitations and diaphoresis. However, a wide range of signs and symptoms may be present. In the cardiovascular system, the most common signs are labile hypertension and sinus tachycardia. Systolic heart failure and ST-segment deviations mimicking myocardial infarction have also been reported, as well as QT interval prolongation and, rarely, ventricular tachycardia. We describe a challenging diagnosis of pheochromocytoma with many cardiovascular manifestations, which could have been missed due to the absence of typical symptoms.

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