Background: A young person's first sexual intercourse is often a remarkable and memorable experience.However, little information exists regarding contextual factors of this first experience and the possible effects ontheir subsequent sexual lifeObjective: This study explored the conditions of and women’s emotional reactions to first sexual intercourse(FSI), as well as FSI’s impact on their future sexual experiences.Methodology: Participants were 899 women aged 19 to 40 yrs, registered in 23 arbitrarily selected GPs privatepractices. They completed a 30-item questionnaire regarding their first sexual intercourse experience.Results: It was found that information sources for sexual issues (family vs media) significantly influence both theadoption of responsible sexual behaviours and the formation of feelings preceding sexual initiation (p<0.05). Thestudy also demonstrated that even when FSI is perceived as voluntary other correlates (e.g. woman’s and /orpartner’s age, contraceptive use etc.) affect women’s emotional reaction to first coital experience and theirresponse to future sexual encounters.Conclusions: The findings of this study provide initial data to suggest that the first sexual intercourse experiencesignificantly impacts women’s sexual life. Health professionals should be aware of this information in thedevelopment of programs focusing on the promotion of sexual health for adolescents or parents; education.