pseudomembranous tracheitis caused by aspergillus fumigatus in the setting of high grade t-cell lymphoma

pseudomembranous tracheitis caused by aspergillus fumigatus in the setting of high grade t-cell lymphoma

;Prashant Malhotra, M.D.;Karan Singh, MBBS;Paul Gill, B.S.;Sonu Sahni, M.D.;Mina Makaryus, M.D.;Arunabh Talwar, M.D., FCCP
current treatment options in cardiovascular medicine 2017 Vol. 21 pp. 42-45
256
m.d.2017respiratorypseudomembranous

Abstract

Pseudomembranous tracheitis (PMT) is a rare condition most commonly caused by fungal or bacterial infection that is characterized by a pseudomembrane that partially or completely covers the tracheobronchial tree. PMT is most commonly found in immunocompromised patient populations, such as post-chemotherapy, AIDS, post-transplant and hematological malignancies. Due to its rarity, PMT is often not included in the differential diagnosis. This case describes a 65 year old male with persistent fever and refractory cough despite high dose empiric antibiotics. Subsequent bronchoscopy with biopsy revealed pseudomembranous tracheitis due to Aspergillus fumigatus in the setting of T-cell lymphoma. PMT should be considered in the differential diagnosis of refractory cough in the immunocompromised population. However, it has been described in patients with nonspecific respiratory symptoms such as dyspnea, cough, and other airway issues.

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ID: 174736
Ref Key: m.d.2017respiratorypseudomembranous
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174736
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10.1016/j.rmcr.2017.03.016
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