Anti-inflammatory Dendranacetylene A, a new polyacetylene glucoside from the flower of Ramat.

Anti-inflammatory Dendranacetylene A, a new polyacetylene glucoside from the flower of Ramat.

Li, Meng;Zeng, Mengnan;Zhang, Jingke;Shi, Jingya;Lv, Jinjin;Tang, Yingying;Zheng, Xiao-Ke;Feng, Wei-Sheng;
Natural product research 2020 pp. 1-7
193
li2020antiinflammatorynatural

Abstract

A new polyacetylene glucoside, Dendranacetylene A (1), and a known compound 8E-decaene-4,6-diyn-1-O--d-glucopyranosyl-(1"→2")--d-glucopyranoside (2) were isolated from the flowers of (Ramat.) kitam. The chemical structures of these compounds were elucidated by NMR and HR-ESI-MS analysis, and comparing these results with data reported in literatures. Additionally, the anti-inflammatory effects of compounds 1 and 2 were evaluated on RAW264.7 murine macrophage cells induced by lipopolysaccharide (LPS). The two compounds significantly inhibited the NO production in LPS-induced RAW 264.7 murine macrophage cells and exhibited anti-inflammatory effects.

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ID: 171932
Ref Key: li2020antiinflammatorynatural
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171932
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10.1080/14786419.2020.1825425
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