The impact of the deforming structure on the human skull is one of the most challenging and debated questions in modern archeology and anthropology related to artificial deformation of the skull. This is precisely why the present study attempts to study the pathological artificially deformed skulls of representatives of the Catacomb culture originating from burial mound in the Lower Volga region. The analysis of the bone material was carried out with the use of X-ray method of the frontal and lateral views. Thirteen radiographs of skulls with traces of deliberate artificial deformation were examined. The skull shapes, structure of the skull calvarial bones, state of the cranial sutures, signs of intracranial hypertension, and symptoms of vascular and endocrine pathologies were explored and evaluated. The study discovered that Catacomb culture bearers used a variety of methods of skull deformation. Front occipital, occipital ring strain and conventional acrocephaly deformation modes were revealed. The viability and compatibility with normal human activity of artificial skull deformation was observed. In the childhood and newborn periods, individuals have applied constrictive and restrictive devices, trusses andother appliancesfor a few years, their impact couldresultin the intracranial hypertension syndrome, as well as in problems with cranial sutures obliteration. It is very much likely that the use of strain could stimulate the development of the internal frontal hyperostosis (Morgagni's disease) which contributed to the emergence of endocrine abnormities in humans. The increased trauma rate of skeleton bones was observed in population of the Middle Bronze Age, as well as ear diseases which makes us once again address the issue of social and cultural phenomenon of intentional artificial deformation of the head tradition.