This paper analyzes the development strategy of population health informatization in China, and summarizes the measurement direction and evaluation elements of population health informatization. Methods: Literature and field investigation, expert consultation and PEST analysis were used to determine the development level measurement and evaluation framework. Results: Based on the PEST analysis framework, the development level measurement and evaluation factors were defined, and the evaluation framework was established, which included system construction, IT application, information financing, information personnel, information policy and management, and information application effect. The information from hospitals and grass- roots medical and health institutions was also provided. From the perspective of the level of development, the framework of informatization evaluation is further refined.