basics of antioxidant therapy in acute pancreatitis (experimental study)
;A. P. Vlasov;A. N. Mitroshin;V. I. Nikolsky;A. V. Suslov;T. A. Muratova
journal of public health management and practice2018Vol. 13pp. 14-18
183
vlasov2018basics
Abstract
The activation of membrane lipid peroxidation, circulatory and tissue hypoxia are crucial triggers for membrane destroying events in acute pancreatitis. The use of anti-oxidant therapy in acute experimental pancreatitis reduces the intensity of lipid peroxidation (the level of diethenoid conjugates statistically confidently reduces by 30.4-32.5%) and restores the tissue respiration (oxidation-reduction potential is above the control one by 10-15%). Such therapy provides less effect on the microcirculation.