With the rapid development of information communication technology and data mining technology, we can obtain taxi vehicle’s real time operation status through the large-scale taxi GPS trajectories data and explore the drivers’ activity distribution characteristics. Based on the 204 continuous hours of 3198 taxi vehicles’ operation data of Shenzhen, China, this paper analyzed the urban taxi driver’s activity distribution characteristics from different temporal and spatial levels. In the time level, we identified the difference with taxi daily operation pattern (weekday versus weekends), continuous time in one day, passengers in vehicle time, and taxi drivers’ operation frequency; in the space level, we explored the taxi driver’s searching pattern, including searching activity space distribution and the relationship between the pick-up locations and the drop-off locations. This research can be helpful for urban taxi drivers’ operation and behavior pattern identification, as well as the contribution to the geographical activity space analysis.