Introduction: To ensure safe, effective and rational prescribing by tomorrow’s doctors it is important to assess the prescribing skills of today’s medical students. The aim of this study was to assess the prescribing skills of MBBS preclinical students of a Teaching Hospital. Methods: First and second year medical students were given different sets of common clinical scenarios and asked to write a prescription for these. The physician and drug related components were analyzed following the WHO guidelines. The data were statistically analyzed using Chi-square test for 99% and 99.99% Confidence Intervals. P values < 0.01 and < 0.0001 were considered significant respectively. Results: MBBS first year student scored 123 (82%) and 94 (62.66%) in physician and drug related component respectively. MBBS second year students scored 139 (92.66%) and 111 (73.33%) in physician and drug related components respectively. Results obtained from the element prescriber's address and telephone number, date of prescription and patient’s address on the prescription of first year and second year medical students were highly significant (p<0.0001). Conclusions: Prescribing skill of first and second year MBBS students is not satisfactory. Prescribing deficiencies were found on both the physician and drug related components which emphasizes the need of adequate prescribing knowledge in order to minimize the prescription errors and irrational prescribing. Based on this study, we suggest all the undergraduate medical students should be regularly trained and evaluated to further help minimize the prescribing errors. Keywords: prescription; prescription errors; prescribing skill. | PubMed