Nurse informatics specialist is the new concept in India moreover it's a kind of challenge in the highly populated All India Institute of medical sciences, a quaternary care premium medical institute in India to digitalise all the medical / administrative paper work. The paper emphasizes on nature of duties for nursing Informatics practicner, desirable skills, challenges and finally implementing nursing Informatics concept in India, in All india Institute of Medical sciences. For the first time the nursing informatics concept is used and implemented in India, and I am the part of this concept. I will be further sharing my experiences of Nursing informatics practice in India.