Electrophysiological measures of expectancy violation processing by the brain, such as the P300 component of the event-related potential, have provided insight into the way in which humans with varying amounts of musical experience maintain representations of musical information, in particular tonal representations. Bischoff Renninger and colleagues (2006) seek to extend this work by examining the P300 in the context of the very interesting topic of cross-cultural music perception, using Western listeners who either have or have not undergone training in Javanese music. Their study highlights the myriad issues and complexities of experimental design and analysis that must be addressed if one is to conduct an ethologically compelling and interpretable study of musical context representations using brain responses as dependent measures.