investigation of fatty acid ketohydrazone modified liposome’s properties as a drug carrier
Abstract
pH-responsive liposomes were prepared by modifying the liposome with acid-cleaving amphiphiles. Palmitic ketohydrazone (P-KH) or stearic ketohydrazone (S-KH), composed of hydrophilic sugar headgroup and hydrophobic acyl chain, was used as a modifier of the DMPC liposome. Because the ketohydrazone group of P-KH or S-KH was cleaved at low pH conditions (
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162004
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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
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162004
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10.1155/2015/481670
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Scimatic Chain (ID: 481)
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