a novel aromatic iodination method, with sodium periodate used as the only iodinating reagent

a novel aromatic iodination method, with sodium periodate used as the only iodinating reagent

;Lech Skulski;Maciej Sosnowski;Piotr Luliński
Journal of ethnopharmacology 2005 Vol. 10 pp. 516-520
145
skulski2005moleculesa

Abstract

Benzene, halobenzenes and some deactivated arenes readily reacted inanhydrous NaIO4/AcOH/Ac2O/concd. H2SO4 mixtures to afford, after quenching withexcess aqueous Na2SO3 solution (a reducing agent), purified iodinated products in 27-88% yields. This novel method of aromatic iodination is simple, fairly effective andenvironmentally safe.

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ID: 161127
Ref Key: skulski2005moleculesa
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