atividade biológica do lapachol e de alguns derivados sobre o desenvolvimento fúngico e em germinação de sementes biological activity of lapachol and some derivatives as antifungal and in seed germination
;Marco Andre Alves de Souza;Andrea Rosane da Silva;Marcio Alcântara Ferreira;Marcela Jacques de Lemos;Rafael Gonçalves Ramos;Aurélio Baird Buarque Ferreira;Sonia Regina de Souza
greece and rome2008Vol. 31pp. 1670-1672
194
souza2008qumicaatividade
Abstract
The natural quinones lapachol, α-lapachone and β-lapachone, and the synthetic derivative β-lapachone-3-sulfonic-acid were assayed for inhibition of fungal growth (Fusarium oxysporum) and germination of lettuce seeds (Lactuca sativa L.). β-Lapachone has the strongest activity as a germination inhibitor and lapachol shows no effect. β-Lapachone, followed by lapachol, are the most active in reducing fungal growth.