simple and efficient synthesis of 2,7-difunctionalized-1,8-naphthyridines

simple and efficient synthesis of 2,7-difunctionalized-1,8-naphthyridines

;A. Adak;A. Maity;S. Jana;R. Mukherjee;R. Mukherjee;S. Goswami
Journal of ethnopharmacology 2005 Vol. 10 pp. 929-936
84
adak2005moleculessimple

Abstract

The syntheses in good yields of some new difunctionalized 1,8-naphthyridines 4, 6, 8 and 9 and a novel triethylene glycol ether-linked dinaphthyridine, 10a, along with the mononaphthyridine-linked ether alcohol 10b are described. An improved and milder method for the synthesis of 2,7-diamino-1,8-naphthyridine (14) is also reported.

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