safety of tumor necrosis factor blockers in adult’s and children’s rheumatologic practice

safety of tumor necrosis factor blockers in adult’s and children’s rheumatologic practice

;T.M. Bzarova;E.I. Alexeeva;S.I. Valieva;A.M. Alekseeva;R.V. Denisova;K.B. Isaeva
Biocontrol science 2010 Vol. 9 pp. 82-94
163
bzarova2010voprosysafety

Abstract

The article presents the review of a safety of TNF blockers in treatment of rheumatologic diseases in adults and children. Authors give a data on separate, open-labeled, and multicenter double-blinded placebo-controlled studies of tolerance to infliximab, etanercept and adalimumab. The results of studies show high effectiveness and good safety of TNF blockers in adult’s and children’s rheumatologic practice. 

Key words: children, rheumatoid arthritis, juvenile arthritis, TNF blockers, treatment, safety, infliximab, adalimumab, etanercept.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(1):82-94)

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