Pilomatricoma is a benign tumor of subcutaneous tissue that arises from hair follicle matrix cells and is usually asymptomatic. Several clinical reports of pilomatricoma have been published in Korean radiology, dermatology, and pathology literature. However, to the best of our knowledge, there have been no Korean case reports of pilomatricoma mimicking male breast cancer. We report a case of pilomatricoma presenting as an exophytic palpable mass in the left breast of an adult male.